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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45862641f0b8f721f19e799f52f31ff4244e68ffeacdcd61532dc32ecd656ba4' 
  AND token = 'yseIUGXdfqFAMbPno5XvvScCEQOf4qrc8QY9eTOrZr0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00051

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}