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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e8f3072f9b6d60900518e188e7c9f9b56f9f133bd4d7f20189d40d8f8596cbcc' 
  AND token = 'qm+0auyLvBfGrJroT7dMR0mODiKaHc59uqsY+IovGgw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}