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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5f0c7bd53b8f0e63a315b0b933b8250cedc5229ebece02d4e88cc70ae0349b1b' 
  AND token = 'p6Cge5MmjlxKkMeeJ2JcHDW5c0cb/mZccrfGClJgE2s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}