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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5018c977189b4237d46f6308cf4a0c11dc462a79ca7c2b82584d39b9b0707d5a' 
  AND token = 'khlSdBOHEOY6uD3lZeuE+HJLvcD3RGvKKePvEl3c4eM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}