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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4f7b573b3f8b1c1153a77862540f333187a575019b94db4c9cc652c3b05c261d' 
  AND token = '1wUcuWRt0XS+govRdjtqAkt6HgNUyGGERPfEhmJ6ER0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}