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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6e43c3f6e05e25be23e1983eb7978246e34e1ab124d7be4a39be8f68e57003fa' 
  AND token = 'RfdZ1Vj1WptOlPyFb3AgfKEmq1wg9k6LMmHw3LSFHQE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}