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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0f3c9352ef40ec1440906d255e95693effb4cd3c7fcabb22705c5893cd92a5b1' 
  AND token = 'ceWWpz+SBDT1EY8m7LCo2fB7ec6ufOQfixq+BKA23a8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}