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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '12640fd5551be3c707ed4dddf1019c2d2fcd125b6325e8516117d24c5e1df145' 
  AND token = 'xU6tVsrYxUg9+BUYPh0KNNfpkhzE8r3RtpK2AJEmSbs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}