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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6a718f1e83f25578705f575e955b87d4cd23b236fd54c9503c28531b74bd153a' 
  AND token = '7OKd3DgGndTWDH9Iv1SsXRfJkX4Tj1MYjfHXDVs0hdo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}