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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8d4bf78887d743b6684128da054420a86c0c27d3e7ff370b7e2364f4b4f2a7d4' 
  AND token = 'BXcLBQ6R4SenEMElj2nGjpgUuGaHelhsCqVXP1MGUMY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}