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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f54f8c20935ce9e3f1e7f290bfe6e31ef1b9d14390defa881c4507b5eea49be4' 
  AND token = 'F37FdZe5+X/hUQy2wgva6G8GFIz7ZmrlKj6m4HFD4t0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00048

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}