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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '64dc715c1b4efcecbd3c08e1037429fcbbe758f1a4202d32cf2237e96b3593a5' 
  AND token = 'a5IxmeLAsNa42McWMWa/ylaWbzoDnJZ9OsGuzSk5FPg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}