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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8c62bf0fba5753d2208a6683a6bd41c87e67b8d1c93077bb31cb7671c857f053' 
  AND token = '1/khAH++jc+/0dUVR90HhYZMdppUZQLjyfUmLG6+FHQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}