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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1b6c84a24637f759c2f77f620a3f4e5ebf390372bf7b210632f60db99d75a6b2' 
  AND token = 'gUumgMhx342PbPpo4Xhlp+x4ajwWXpG2XNmuNqAfo44=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}