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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0f018c53e83f0b19129882a186bf1baa5753653a7fc51a482faf78f03e497991' 
  AND token = 'njAdp0hKAZII7yDpMFLyNcpTLlckuEFjP4+NwkLoPpk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}