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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0f7059261345c10c3d4ca5e719c27d1ddb39dea9856dd7f95f95cb162a9b03a1' 
  AND token = 'E3O6TgI5x9aCk7cbTOO0CQjRywCm2dh1QZ1y3f07Qfo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}