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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '42c8527acfe144ab5dc20dfdea795efaaa384ab6a16b45875adc5e98d720dc3e' 
  AND token = 'ZzxdW+ihh5imoOr4Qs2AO0YMgPsRl2W56HPFsiqxKEE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}