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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c66b18d878331049cb520fbd72776ee4a0d29de251d3c83b299b3bc2f11f201a' 
  AND token = 'sjKPZg2SZulRmmuQdBqI8RMiGNcJA7sWL9bROirREC4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}