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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '42f8e507b4f0e9948586d29328f409bf09ab5bcdd084abce4a4a4624bad3abbe' 
  AND token = 'CZCPVHMA4jGdCV/GeTVRp9Ys0DlnDA187/hW6rmmK9Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}