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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'aa4b068e7b4a15d5abdf0f39a59c232f67c52d1b01300b677d0376edb2cf8a66' 
  AND token = 'IZJHbXS67M5gQCt8rpDCALGwGiUJyX3uH7+4tpxbPNo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}