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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ea8ec848276780b8e7fec74eff31f067f4aed3d535398b8d09096961935bd743' 
  AND token = 'FVncUWPFXc3phoURiZWFYM6VJ6knYVM0JSD+yYcy+vM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}