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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '25a820e0481f700220c7e796530db35851e0e2031b880883419e119ad40bf91a' 
  AND token = '3muyrazEO6MRV7aFdeGbUvjJnsy73K+1nkWQ0EREZ0M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}