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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f6e38a1946c92c6a1f0a597d5829394460d3771bfe2411d9cd80c5d5340cde1f' 
  AND token = 'hiHq85TmxSQfJwpU+Wie6NbBa44Aqzz0avaE07IpTDI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}