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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5c27557d7cfd614bbe1d45f8522f6dcd663c64d0634be70eda30a32c5a2605d0' 
  AND token = 'V5jeTtOARXvvEsC8KjAha/yVmUyzUEh3jxCPN/Z6AP0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}