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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '72477ec259951b42cb599ed943aeb098c924a057b3279633c3b3eabe6653eb4d' 
  AND token = 'gdtjo6o+FfmWkzcru6mEc2TJnhdiYW6a8RRtV5E2DWo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}