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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3d6bd310def0a28fcda731137dd21cf6a34ce88ebfb877164cc69066fa43cf5d' 
  AND token = '0y2mJV92/hsXuyT6lgBMAoKtUt2fOsgO2+ZB0m0OdJI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}