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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '48afe274afbe8ec0f2857011623ebb6d4ebe295e5b17967dea0529b9771f92b3' 
  AND token = '/dztv5vaTUYLCAXJL6f8gMzA/8VVE3crknq8o53egYc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}