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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '55de805427cf706ed5cffa8fdec9acf6e2b93223fd8b315d32cc6f795a2a3377' 
  AND token = 'V7Zu4ySn+Oycl9/ZOUy0gZFr+r3lh0qoUF5CpKHHNg0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}