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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '287500eae6d757d4c4b86b359af1629d3436eb53445698bdde64f553cd00950c' 
  AND token = 'CDN1EUSUkt8DVRvn6tuQBmHW/zl0l7fzVVHxVXqJo0I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}