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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e5531db2984c65f1bd12b1a2162538be665fc43a8d4d6f21ca8302b4b49b9992' 
  AND token = 'E/WrXxnhu2WG8Xmaou1zfEPBDGRVnEhGyrhsTP6p8UI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}