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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '11db1d53c7522e6bf43d9b46bfa17724e9e8621db1b13ead09517d1af1a22bfd' 
  AND token = '4dTOmXxk/T09nXxhtNOzAhPFpLCqkRIJ33UNP04aCqw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}