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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0a10db6df6263c5865f373d7214262c599e59cc64265724d298cdcfda7c172e2' 
  AND token = 'jxUHQiS5Edu+5tbZ9G9zbJe0GtNdywzsdm26ET4d9pQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}