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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c37767a68d16c3b23c03635c3a9a16141c48f51e14c6090bfb91ca67199516f8' 
  AND token = 'vazZE3tWcEfE2VUSpNCdvxuiZxbOtIT/nIdTnM66TWU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}