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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e4c3ab9cea985cca436e783563869077c10fa552070e96cb4c62e65e732ae441' 
  AND token = 'ObYoeyGMlc5iUro43h3CYGAL9UJH5ufl16dJVE684/A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}