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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd03782ecacf97f5ab779c7a0aa72c187beacde6489ebb0169e7a369c6d6258aa' 
  AND token = 'E1Fvm7xrx9QXZ0TsMld2OoYt/KNzet9sTDXZS8T6rdw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}