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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1ded104644be27d22e638f24ba3bfbf5d3a97b80ab52081b9367d9e000ae2df1' 
  AND token = 'QAiiQVcH05VNn3a0XmfPe5JXyjMoSOLzxOPChVniJ3w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00050

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}