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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '16e86390da9464b0ad91a3f0f5991b51fc785bba610caf7c0ea9993117083add' 
  AND token = '0ALBJXHjxVW+Pamf1Uo7f7IhgTsHluTcsr7B6LzUhg0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}