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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e6358e41da4ef15384de9dda949f017281622ff3e1d64f0f770369fc9be85b1e' 
  AND token = 'yHjN1ORU9WEQxnbh5jKu3fGzrHhUrm9YRPmJQE2i/xE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}