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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '936d204fc7bf0fa22c0c9c1337b500db479bb18e887e11eb5731092e8e04a5dc' 
  AND token = 'eMrkVGvRbqkWxaAQUFsPEQnOaTJzBpCv+tjkHxvnlnA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}