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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5e00eed1b6f75623c3ae0df7d5fb00324406327495bbd2a6e33000f458234584' 
  AND token = 'HGhj+2R3UyCQjTuzZ/ScdCQNssYngjvUA1lv9iMNl0M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00061

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}