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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8f889c799a333f995d3e3c58eada223ad311a0e8d20405bd5d10bf709e37bb74' 
  AND token = 'ZWYdEs+GX3jjOydXPGumVXZ67AdggWDcTPMf9ROZ5LU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}