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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5496d235484b6f5cca49d755ef38e793759dbf7418a8dc0a56f9ef3fc533a194' 
  AND token = 'MhYlowa+H1Yx97sMdws48GpycV5IbFibf3nXudaru10=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}