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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c6efd2dde5b0637948d8667c018273ff3226d76fa1d5cb309090d3feba9fcdfd' 
  AND token = 'KStQ23VQb9L6NZDHE/4m14wgK5P8ihAxQtPpp4PETLc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}