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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '740aec10abef92f20a1f743149f8adf38297acd541a9008f3d4ef141a549b490' 
  AND token = 'xdmk/QNDiJ/6ngkNB7gn+l8VuN7mNRFvZAx/4bM67Do=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}