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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4a37cedca54be6c211664c5ceeecebba74014ed984d0aaaab8cbc00b3c491808' 
  AND token = '3GSDTX6X4Rci53eI2k9kszlfLgUDKvS8l4MFK4TZ81w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}