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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '315746f7a81371d5960008f0f3e0af72cbe7e89bde2d1b477467828bc5b0a7c6' 
  AND token = 'pZJTqSBi32OLfBbVywFMogSvDSVlp8ukQQEK7IStIic=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}