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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '69b6c51f2c611475c32010103babb6fcf78a00b3f14aa01439721639c58a307d' 
  AND token = 'ot2M0m4Kh6+KcHuqScsZYHGXmxC8C9eu0G2CISjOar4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}