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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a2df5ed9143ce759288e5aeb6d6b33594dd2577e9f6ac7412f7c175520a80021' 
  AND token = 'PcLXAQBZVrMWjmP0hS/Tij7gWwofC0aUb/GaES5ke6Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}