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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9c0f656695aebf67f3f378eed2dc77c8924da6301a60811eacbcf12af79a4613' 
  AND token = '2T8EbNZ2RSa9SWpiKiEcq7VtCLgmlVRDDPSdL78iCZ0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}