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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5a2f5f1b32178b21fc2db54cb930a884aa93375e75529bdbded517ab5a8b5bdb' 
  AND token = 'Sp3IeEwJUTxbvpY00E1BfoSV8/2GDu4UuFfRYYtuU24=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}